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6 Tips for Better Health

Posted By John Gannage, MD, Wednesday, January 25, 2012
Updated: Thursday, January 30, 2014
1. DRINK WATER. There is not a more important, or inexpensive, endeavor physically than replenishing our bodies of clean water. All of our systems require water to function optimally - our cells bathe in it, wastes and nutrients flow because of it, our detoxification systems rely on it, digestion is impaired without it. At times chronic headaches and low back pain are related to water deficiency. We are 80 % water in our physical makeup. Two litres per day for most people is required; or take your weight in pounds, divide by 2 and drink that amount in ounces (e.g. a 150 lb woman would drink 75 ounces daily). I suggest avoidance of chlorinated drinking water. Re-mineralized reverse osmosis is a good choice.

2. A SALAD A DAY. At my clinic I routinely conduct a diet review with all new patients. I consistently find, especially in patients that are chronically fatigued, chronically pained and/or chronically constipated that, not only is their water intake diminished, consumption of fresh fruits and vegetables is much reduced. North American diets are horribly inundated with refined, packaged, nutrient poor foods, white flour and refined sugar. Eliminate these, and replace them with fiber, nutrient dense leafy greens and other vegetables. For those that have a challenge with gas and bloating from fruits and vegetables, a reasonable approach is to start with steamed vegetables. A useful intervention is digestive support, as with enzymes, during meals, and avoidance of food sensitivities.

3. CHOOSE ORGANIC. Organic food has made its way into the marketplace for healthy reasons. Foods high on the food chain concentrate chemicals and hormones in their tissues, and yet we require many such foods for optimal nutrition balance. The dominance of hormones in our food supply accumulates progressively in our own tissues, leading to problems with reproductive tissue structure and function, and ultimately to the worst kind of pathology: cancer. Antibiotic use in livestock takes place at a huge cost to human health, affecting bowel flora balance and contributing to reduced effectiveness of antibiotics when required to fight life-threatening infections (i.e. antibiotic resistance). Organic food has been shown to possess 40% more nutrients than non-organic counterparts, since chemicals negatively impact soil richness. In Canada, our largest exposure to pesticides comes from our standard diet. One's greatest defense against environmental toxicity in general is nutrients. Our diets, therefore, must be sources of nutrients, not chemicals.

4. PAY ATTENTION TO SYMPTOMS. Ignore, or worse suppress, symptoms at your own peril. Headaches, bloating, gas, fatigue, muscle pain, frequent colds, skin rashes and so on are all signs of an underlying disturbance calling out for correction, not mere suppression. Track symptoms, listen to your body, and learn to describe them in detail to a health provider who will listen. The greatest amount of information about one's health comes not from lab tests or scans, but from symptoms interpreted meaningfully.

5. BE KIND TO YOUR LIVER. Sub-optimal liver function lies at the core of many medical symptoms. It is an organ with multiple roles, from detoxification, to digestion, to hormone metabolism, to regulator of circulation. Being kind to the liver means avoiding undue exposure to chemicals, both in the diet and around the household. It means paying attention to healthy intestinal function, thereby reducing bowel toxicity and autointoxication. It means using probiotics routinely, and other supplements, particularly antioxidants and herbs, that are therapeutically supportive to liver functions. It means understanding Eastern medicine concepts detailing the liver as an emotional organ, and its connection to anger.

6. PRACTISE ACTIVE LIVING. Exercise has innumerable health benefits, for mood and sleep, for immune system strength, for cardiovascular function, for sweating and detoxification. A sedentary lifestyle is a choice for chronic medical conditions, and the options for inactive living are far too accessible. Computers, television and video games, combined with unhealthy snack foods and drinks, have assisted the development of our current pediatric obesity epidemic. Over 50 % of adult Ontarians are overweight and obesity is now recognized by experts as the second-leading preventable cause of death after cigarette smoking. For most of us, overweight or not, active living can also mean taking the stairs, raking the leaves, parking further away, or not driving at all. It is time to get back to active living, to get off the couch or desk chair, and to breathe some fresh air outdoors.

Tags:  health  nutrition 

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An Expanded View of Prenatal Care: 11 Points to Consider

Posted By John Gannage, MD, Saturday, November 19, 2011
Updated: Thursday, January 30, 2014
Prenatal care from a conventional medicine perspective follows a standard that is an excellent starting point. Tobacco and alcohol restriction, measuring iron levels, checking fetal structural development, BP and urine measurements, and other aspects of primary care prenatally are important pillars. With more funding, and if asked to direct a higher standard of care, these are the additional recommendations I would make:

1. Disseminate information to would-be parents,prior to conception, that a pre-pregnancy session with a trained professional is advisable.

2. During the pre-pregnancy session, an individualized treatment plan would be outlined by a holistic professional, with the intention of optimizing mom's health. This session could be used to understand Mom's lifetime habits and exposures, address nutrition imbalances, optimize liver function, provide support for digestive and intestinal health, and detoxify tissues following the principles of functional medicine. Setting the target date for conception based on a measurable change in Mom's health would be advised. (The same process can be used for Dad based on research indicating the importance of sperm health.

3. During the pre-pregnancy session, a discussion would take place emphasizing the importance of: a balanced diet; the avoidance of dietary chemicals like high fructose corn syrup, MSG and aspartame; assessment and avoidance of food allergies, intolerances or sensitivities; organic food choices with direction on avoiding "the dirty dozen"; the best fish choices; and the basics of hydration including the healthiest water sources.

4. A home survey would be conducted, with education about: the importance of avoiding home renovation projects during, and perhaps prior to, pregnancy; cleaning up indoor air quality; the common sources of household lead; and the strict avoidance of chemicals like pesticides. Scanning the home for EMF's and geopathic stress could be included.

5. Aworkplace survey would be included as well, again with the purpose of identifying and avoiding sources of poor air quality, excessive radiation, and oxidative stressors.

6. Provide sound advice about dental procedures and cleaning during pregnancy where amalgam fillings are involved.

7. Check Mom for an Omega 3 score, and optimize Essential Fatty Acid balance. EFA's are vital to fetal nervous system development.

8. Measure Vitamin D blood levels, and supplement into a healthy range, while also avoiding calcium deficiency.

9. Aggressively treat iron deficiency, which along with point 8. helps to avoid/lessen the impact of stored bone lead mobilized during pregnancy.

10. Measure and ensure normalcy of Mom's glutathione and/or homocysteine levels.

11. Instruction on appropriate physical activity, air travel, emotional stress and other impactful daily activities that are often taken for granted.

This is a list that can be expanded as research develops regarding how to best protect a developing fetus from any negative influence of environmental and nutrition factors. It is based on personal experience in my medical practice where taking detailed case histories, including pregnancy exposures, of a tremendous number of families has been part of my daily routine for over 10 years.

The goal is ensuring the healthiest newborns and children possible, understanding that studies have shown that at birth 287 chemicals have been found in cord blood For some children, perhaps the ones with susceptibilities or compromised nutrition, a chemicalized start to life inside, and then outside, the uterus is a contributing factor in developmental disorders.

Parents are advised to bear in mind that fetal tissue concentrates many chemicals to a much higher level than what exists in Mom's tissues, that many chemicals move to the baby from Mom during pregnancy, and that the blood-brain barrier is not fully developed until at least 6 weeks after birth. A little education in this area can go a long way, which in my mind should begin prior to conception. Because the question needs to be asked: are we as a society, in the 21st century, doing all we can to ensure a healthier start for our newborns?

(Dedicated to my kids)

Tags:  integrative medicine  nutrition  prenatal 

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Breast Cancer and Nutrition

Posted By Andrea Purcell, ND, Wednesday, October 12, 2011
Updated: Thursday, January 30, 2014

October is breast cancer awareness month. There are walks for breast cancer sponsored by various groups; many working to find a cure for cancer. A walk I recently attended was with Support Connection, a non-profit organization providing free support services for women with breast and ovarian cancer.

From a Naturopathic perspective, preventing cancer is the first step, curing and or surviving cancer is the second step. It seems as if many people miss the first step, and by the time they get to the second step there is a lot of fear involved.

There is some basic information that will keep you informed about how to prevent breast cancer and why conventional medicine often provides a false sense of security around this topic.

Point #1: Nutrition is important. Sadly, more often than not I come face to face with women with cancer and close family members who do not realize that nutrition has an impact on survival rate and overall health. Sugar feeds cancer cells and it lowers the immune system. Gluten and dairy products are inflammatory and will cause more inflammation slowing down the cellular repair processes. Certain vegetables such as dark green leafy greens, kale, cauliflower, broccoli, Brussels sprouts, and parsley have chemical compounds proven to prevent and fight cancer. Artificial colorings, flavorings, dyes, hormones, and preservatives in food are often suspect carcinogens.

Point #2: Most conventional doctors do not discuss nutrition with their clients. Nutritional biochemistry is not taught in conventional medical schools. The reason your doctor most likely did not discuss nutrition with you is because the importance of it is not stressed in medical schools.

Conventional doctors do two things very well:
Diagnose and treat disease with drugs and surgery. The key word is disease. If you have a disease they will either recommend drugs or surgery. If you are trying to prevent a condition that you don’t officially have yet, it means your conventional doctor can’t help you. Conventional doctors diagnose and treat diseases only. If you want to know how to help yourself with nutrition, or pursue natural therapies to help your body, do not expect to get all the information that you need from your conventional doctor.

Point #3: Mammograms do not prevent cancer, mammograms screen for cancer. A mammogram will not tell you if you will develop cancer next year or evaluate the current health of breast tissue. Therefore, mammograms have limitations. If you are relying on your annual mammogram to give you the green light, for another year of bad nutrition, and lack of exercise, think again. Wouldn’t it be a good idea to make some healthy lifestyle changes now? As Benjamin Franklin said, "an ounce of prevention is worth a pound of cure.”

Mammograms are not recommended in younger women for two reasons:
Reason 1:Younger women can have denser breasts, which create less visibility and therefore less accuracy on a mammogram.
Reason 2: Mammograms are x-rays. Repeated radiation of breast tissue can accumulate in the body and cause cellular damage to breast cells. X-rays are known carcinogens. Receiving a note that your annual mammogram is negative provides a false sense of security to a woman who may have some pre-disease states manifesting that will ultimately impact the health of the breast tissue.

Note from Dr. P:
As usual, naturopathic medicine has the other side of the story.
Nutrition, nutrition, nutrition, I can’t stress this enough! How can you expect your body to perform optimally for 40+ years on Frappuccino’s, lunch at the local sandwich shop, and take out? It just won’t. Yet, I see some highly educated women out there who put everything before food, nutrition, and feeding themselves. This has got to stop! Food is our gasoline; it provides the fuel for every body system. Usually we can "cheat” up until age 40 but as usual, you can only make withdrawals from the body for so long before it becomes bankrupt. I call it nutritional bankruptcy. From this point, we go into accelerated aging, the development of chronic diseases, hormone imbalance, depletion, and we are left wide open for cancer and other undesirable conditions.

Whole food is food that grows. When you are reviewing ingredients and food choices, ask yourself, have I ever seen this growing on a farm or in the soil? Hint: Frappuccino’s don’t grow on any farm anywhere.

Mammograms are an important screening tool, yet they need to be properly understood in order to see the whole story. Breast health is an indication of whole body health; the breasts cannot be separated from the rest of the body. Naturopathic medicine has a lot to offer women with pre-existing hormonal imbalances, which will enhance the health of breast tissue over time, reduce fibrocystic densities, and prevent cancer.

- Be Healthy, Happy, and Holistic

Tags:  cancer  nutrition 

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CoQ10 for Migraines

Posted By Rosemarie Salo, Pharm.D., Wednesday, October 5, 2011
Updated: Thursday, January 30, 2014
Peer Reviewed by: Brian Solow, M.D., FAAFP

Migraine headaches are a common, chronic, debilitating neurovascular disorder. Migraine attacks may start at any age, but the incidence peaks in early to mid-adolescence. Overall, the one year prevalence of migraines is 11 percent: 6 percent for men and 15-18 percent for women in the United States and Western Europe. The frequency of attacks is 1.5 per month and each attack lasts about 24 hours. About 10 percent of patients have weekly attacks, and 20 percent have attacks lasting for 2-3 days.

Five percent of the general population has at least 18 days of migraine per year, and about 1 percent has at least 1 migraine attack per week. Most patients in the United States have not seen a physician for migraines during the previous year, nor have they been given a medical diagnosis for migraines. Most of these patients use over-the-counter medications versus prescription drugs due to side effects associated with conventional therapies.1 The side effects include, but are not limited to, dizziness, somnolence, impotence, fatigue, dry mouth, and weight gain.

Treatments can be divided into nonpharmacologic and pharmacologic therapies. Non-pharmacologic therapies include lifestyle changes such as eliminating food triggers, obtaining regular sleep and exercise, avoiding high stress situations, increasing relaxation methods, becoming educated of the disorder, and knowing of treatment options.

Pharmacological therapies that are usually prescribed for acute attacks include NSAIDS, ergot derivatives, and triptans. Patients who suffer from frequent, long endured, severe attacks should be candidates for preventative therapy. Preventative therapy is recommended when the frequency of attacks increase, or when the attacks become unresponsive to acute therapy.

Types of medications used for preventive therapy include beta-blockers, valproate, and tricyclic antidepressants. Other promising drugs include gabapentin and topiramate. On average, two thirds of patients who have been administered these types of medications have had a 50 percent reduction in the frequency of migraines.1

A mitochondrial defect is thought to play a role in the pathophysiological mechanism of migraines based on MRS4 and DNA5 analysis taken from a subset of individuals. Coenzyme Q10, also known as ubiquinone, is a naturally occurring substance and an essential element of the mitochondrial electron transport. Coenzyme Q10 may have clinical benefits for hypertension, angina, heart failure, and diabetes. Doses up to 600 mg per day have been well tolerated. If a mitochondrial impairment does in fact play a role in the pathophysiology of migraine headaches, coenzyme Q10 may be used as a medication for preventative treatment. An open label trial was conducted by Rozen et al. (2002) to assess the efficacy of coenzyme Q10 as a preventative therapy for migraine headaches. The study encompassed a total of thirty-two patients (26 women, 6 men) with a history of migraines with or without aura. Subjects included in the study experienced between two and eight attacks per month, had a 1-year history of migraines, and had not
received medications 2 months prior to the trial. During the study each subject was given a dose of 150 mg every morning of coenzyme Q10. Each subject was also given a diary to assess their attacks addressing symptoms, duration, and severity. Standard laboratory studies were conducted baseline and after 3 months of coenzyme Q10 administration. The percentage of patients who achieved at least a 50% reduction in the frequency of headache days after coenzyme Q10 administrations was the primary outcome measure.

Thirty-one out of thirty-two patients completed the study. One patient was lost to follow up. A minimum 50% reduction in the number of days with migraine headaches was seen in 61.3% of the subjects, and a minimum 25% reduction in the number of days with migraines was seen in 93.5% of the subjects. No improvement with therapy was seen in only two subjects. The average duration time for each migraine declined from 7.34 to 2.95 days after 3 months of therapy (P<0.0001). The mean frequency of attacks (mean number of migraine attacks in the last 60 days of treatment) declined from 4.85 baseline to 2.81 by the end of the study (P<0.0001). After 1 month of treatment the mean reduction of migraine frequency was 13.1% and increased to 55.3% by the end of the study. Coenzyme Q10 was equally effective in patients with or without aura. In addition, no significant adverse effects were associated with the administration of coenzyme Q10, and coenzyme Q10 was well tolerated.

Based on this study, coenzyme Q10 appears to be a promising choice for migraine prevention. Placebo-controlled trials are now warranted to determine its true efficacy in migraine prevention. Patients may choose not to use conventional types of medications due to side effects such as impotence and fatigue. Until further studies are conducted, coenzyme Q10 should be considered for patients who have failed conventional therapy without concern of significant risks.

Coenzyme Q10 is available as 300mg softgels from the McGuff Company.

1. Goadsby P, Lipton R, Ferrari M. Migraine current understanding and Treatment. N Engl J Med 2002; 346(4):257-70.
2. Rozen TD, Oshinsky ML, Gebeline Ca, et al. Open label trial of Coenzyme Q10 as a migraine preventive. Cephalalgia
3. Welch K, Ramadan N. Mitochondria ,magnesium, and migraine .J Neurological Sci 1995; 134:9-14.
4. Montagna P, Cortelli P, Barbiroli B.Magnetic resonance spectroscopy studiesin migraine. Cephalalgia 1994;14:184-93.
5. Bresolin N, Martinelli P, Barbiroli B et al. Muscle mitochondria deletion and P NMR spectroscopy alterations in migraine
patients.J Neuro Sci 1991;104:182-9.
6. Collins C, Kemper K. Co-Enzyme Q10(CoQ10 or Ubiquione). The Longwood Herbal Task Force and The Center for
Holistic Pediatric Education and Research. Peer Review performed by Brian Solow, M.D.,FAAFP, Clinical Professor of
Family Medicine, University of California, Irvine, College of Medicine

Tags:  migraines  nutrition 

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The Real Issue with FAT

Posted By Matt Angove, ND, NMD, Monday, October 3, 2011
Updated: Thursday, January 30, 2014

Are your eating habits making you FAT?

For the average "weight loss” specialist, calorie reduction and exercise are the mainstay of their weight loss programs. I think the best word to describe the plight of most people trying to lose weight is FRUSTRATION!

This frustration is due to the fact that the weight loss program being practiced is not going to lead to lasting weight loss. Lasting weight loss or much more importantly FAT loss requires a complete transformation of daily habits. It also necessitates finding the real issue (aka cause) for fat gain.

When it comes to weight loss, you can be so right and yet be completely wrong.

As I have seen it, the focus of people trying to lose weight is set on "low-fat” and "sugar-free” foods. On the label, it looks like a dieters dream but in the body, it is an inflammatory mess. And if the pro-inflammatory effect wasn’t enough, these foods aren’t satiating, and many of them even trigger hunger signals.

Fat cells generate inflammatory chemical messengers (called cytokines), and those chemicals eventually trigger a reaction for cells to stop listening to two important hormones: insulin and leptin.

So, if you are going to bump the FAT forever, you have to get the inflammation under control. Inflammation decreases the cells sensitivity to insulin and leptin.

When cells become resistant to insulin, glucose gets converted into fatty acids and stored as fat instead of being used as energy. NOT WHAT WE ARE LOOKING FOR!

When the hypothalamus becomes resistant to leptin, the hormone that indicates satiety, people will consume more calories than necessary. Also, NOT WHAT WE WANT!

As a dietary starter, this requires eliminating foods that are inflammatory, such as processed sugars, synthetic sweeteners, hydrogenated oils, over-cooked foods, and foods a person is allergic to. You can make it really easy on yourself by simply just eliminating food items that come in a box.

In addition to switching to a whole foods based diet, specific anti-inflammatory nutrients should be added. Omega-3 fatty acids and probiotics should be at the top of the list, as well as magnesium, curcumin, and ginger to name a few.

This is what we call a long-term, sustainable solution!

Tags:  nutrition  weight 

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B Vitamin May be of Value in Ovarian Cancer and Breast Cancer

Posted By Nalini Chilkov, LAC, OMD, Thursday, September 8, 2011
Updated: Thursday, January 30, 2014

Niacinamide, a B Vitamin, may be of value to women with genetic risk of Breast Cancer and Ovarian Cancer.

Why are some women more prone to developing breast cancer and ovarian cancer? This is a complex question. Every person and every cancer constitute a unique and complex set of contributing factors.

One factor, related to genetics, is the inability to repair damaged DNA(damaged genetic material inside the cell) effectively. Damaged DNA, like damaged software, will send out incorrect operating instructions to the cells in our body. This can lead to uncontrolled growth and the development of cancerous tumor cells.

For those patients with genetics that lead to inefficient and poor DNA repair who are therefore at high risk for aggressive cancers there is a new class of drugs called "PARP inhibitors” undergoing research and approval. While waiting for PARP inhibitor drugs to finally be approved and available studies have demonstrated that the B vitamin Niacinamidealso acts as a PARP inhibitor in doses that yield a pharmacologic effect. Studies used 1.5 grams (1500 mg) three times daily. PARP inhibition allows damaged DNA in the cell to be repaired. Cells with damaged DNA are prone to develop into malignant cancerous cells.*

Women who are positive for the BRCA1 gene are known to have poor DNA repair. These women may benefit from PARP inhibitors. BRCA1 is associated with aggressive and often lethal breast cancer as well as colon cancer.

Recently another gene associated with poor DNA repair has been identified.This gene, RAD51D,is associated with increased risk for ovarian cancer. PARP Inhibitor drugs as well as Niacinamide may also be of value to these women.

Here is an excerpt from article that appeared in Reuters Mon, Aug 8 2011By Kate Kelland LONDON (Reuters) – Women who carry a faulty copy of a gene called RAS51D have an almost one in 11 chance of developing ovarian cancer,scientists said on Sunday in a finding they called the most significant ovarian cancer gene discovery for more than 10 years.

Tests to identify those at highest risk are expected to be available within a few years, according to Cancer Research UK, and may lead some women to decide to have their ovaries removed in order to beat the disease.

The finding should also speed the search for new drugs.

Laboratory experiments already suggest that cells with faulty RAD51D are sensitive to PARP inhibitors – a new class of drugs designed to target cancers caused by faults in two known breast and ovarian cancer genes, BRCA1and BRCA2.

For the latest study, researchers from Britain’s Institute of Cancer Research compared the DNA of women from 911 families with ovarian and breast cancer to DNA from a control group of more than 10,000 people from the general population.

"Women with a fault in the RAD51D gene have a one in 11 chance of developing ovarian cancer,” said Nazneen Rahman of the Institute of Cancer Research and The Royal Marsden in London, who led the study and published its findings in the journal Nature Genetics.

Ovarian cancer can remain hidden for a long time and thus is often not discovered until it is advanced.

An estimated 230,000 women worldwide are diagnosed with ovarian cancer each year. Most are not diagnosed before the cancer has spread, and up to 70 percent of them die within five years.

Speaking to Reuters in a telephone interview she said the identification of RAD51D pointed to PARP inhibitors as a new class of drugs that might offer fresh hope. Initial tests in the laboratory found that cells with faulty RAD51D were highly sensitive to this class of drugs.

"PARP inhibitors work because they were designed to target DNA repair pathways,” she said. "They haven’t been used in patients in that context yet but we would predict they would behave in the same way.”

SOURCE: Nature Genetics, online August 7, 2011.© Thomson Reuters 2011. All rights reserved.

*Niacinamide Monograph Alternative Medicine Review December 2002

Always consult your physician regarding any nutritional program. These statements have not been approved by the FDA and do not constitute medical advice or treatment which is between you and your physician.

Tags:  cancer  nutrition 

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Tips for Healthy Eating

Posted By Andrea Purcell, ND, Tuesday, August 16, 2011
Updated: Thursday, January 30, 2014
Many of the patients who come to me initially do not have good diets. They may be too busy to shop and prepare meals, or not know how to prepare healthy food on the go. By the time someone ends up in my office they have a medical necessity and are in desperate need of a dietary turnaround for their health.

If someone has been eating poorly, I try to make food adjustments that are better but not perfect so as not to overwhelm him or her. In light of that attempt on my part, occasionally when I present a person with an individualized food plan they may become overwhelmed. This depends on the individual. For some, dietary changes are exciting and for others they can be down right daunting.

In this blog I am enclosing my 8 food tips to help someone shift towards a new dietary practice. Read on…

1) Start slowly: Read over the entire food plan and go on a shopping field trip to the local health food store, farmers market, or Trader Joes. Browse through the aisles; compare what the plan says to what you see on the shelves. Check out the vegetables, which ones would you normally bring home, try something different.
2) Focus on breakfast: Read the food plan and incorporate changes to your typical breakfast routine each morning during week one. Do not change lunch or dinner until the following week. Really work at becoming familiar with your new breakfast routine.
3) Simple and delicious: Keep meals simple but hearty. For example plain quinoa flakes can be dressed up with chopped apple, walnuts, flax seeds, stevia and cinnamon.
4) Invest in a good cookbook: Check out my cookbook,Feed your Cells!What can I say I’m biased, for years my patients asked me to recommend a good cookbook and I couldn’t so I wrote my own.
5) Get Inspired! Ever go to a restaurant, have a fantastic meal and try to re-create it at home? Well do it!
6) Think Positive: Instead of feeling deprived, think about how all of the new adventures in vegetables that you are having is helping your body to detoxify and ward off cancer.
7) Make one meal go a long way. You will read about this in my cookbook but there should always be leftovers for lunch. I will cook a pot of lentils on a Sunday and have them over quinoa and spinach for breakfast and lunch for two days in a row. That saves a LOT of time.
8) Transition from fake to real. Ask yourself does this food grow out in nature? Have I seen this food on a farm? If the answer is yes, then it is probably real. Real food gives us life.

Note from Dr. P:
Remember when you were a kid and learning to ride a bicycle? You didn’t ride that bicycle perfect the first time you tried. For some reason when we become adults we do not give ourselves the compassion of trial and error. We become impatient with ourselves when something is difficult. Healthy eating is a necessity, you pay now or you pay later. When you are ready to embrace good health, the path reveals itself. Adapting to a new way of eating and adopting new food behaviors take time. Try to break it down into bite size pieces and before you know it you will be shopping, cooking, and eating healthy, nutritious food. Looking for healthy recipes?Buy my book!

-Be Healthy, Happy & Holistic

Tags:  health  nutrition  weight 

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How is Your Glutatione?

Posted By Matt Angove, ND, NMD, Thursday, August 11, 2011
Updated: Tuesday, February 4, 2014

In 1994, theJournal of Nutritional Biochemistrystated, "Disease states due to glutathione deficiency are not common.”

Well, 25 years and 90 thousand journal articles later we have found this statement to be false on all levels. Glutathione is recognized as an extremely important intracellular antioxidant that also plays a central role in the detoxification and elimination of potential carcinogens and toxins. Studies have found that glutathione synthesis and tissue glutathione levels become significantly lower with age, leading to decreased ability to respond to oxidative stress or toxin exposure.

The higher the glutathione peroxidasein the plasma or red blood cells, the more your body is running through and out of glutathione. Now consider the follow…

Total glutathione peroxidase activity was elevated in females 65 years of age or older. Cigarette smoking significantly elevated glutathione peroxidase. Alcohol elevated glutathione peroxidase, with the highest levels seen in drinkers who also smoked. Increased glutathione peroxidase was also seen in vigorous exercise, especially triathletes and marathoners.

According to the National Cancer Institute, dairy products, cereals and breads are low in glutathione. Fruit and vegetables have moderate to high amounts of glutathione. Frozen versus fresh foods had similar amounts of glutathione. Processing and preservation resulted in considerable loss of glutathione.

A 27% reduction in glutathionehas been reported in the cerebrospinal fluid of schizophrenic patients.

Studies have shown that dietary glutathione enhances the metabolic clearance and reduces net absorption of dietary peroxidized lipids, which cause intense cellular damage.

High altitude exposurereduces glutathione levels.

Glutathione functions as an antioxidant and can maintain vitamin C in its reduced and functional form.

Chronically low glutathione levelsare seen in premature infants,alcoholic cirrhotics and individuals with HIV.

Glutathione increases sperm motility patterns and sperm morphology. In a double-blind, placebo-controlled crossover trial of infertile patients, patients were randomly and blindly assigned to treatment with one injection every other day of either glutathione at 600 mg or an equal volume of placebo. All the glutathione selected patients showed an increase in sperm concentration and a highly statistically significant improvement in sperm motility, sperm kinetic parameters and sperm morphology. Want to get pregnant? Make sure your husband has optimal levels of glutathione.

From the journal of Digestion: Glutathione is extremely important in normal functioning of the pancreas, being needed for normal folding of the proteins that will ultimately form key digestive enzymes when the pancreas is stimulated after a meal. In patients with chronic pancreatitis, it has been found that glutathione is often significantly depleted, suggesting that lack of glutathione has a role in the generation and/or maintenance of the disease. In addition, many patients suffering from chronic pancreatitis appear to be under xenobiotic or oxidant stress, creating an evengreater need for glutathione. Since the pancreas is under relative glutathione "stress” during the normal process of packing and secreting digestive enzymes, it is easy to see how the lack of glutathione could have a role in chronic pancreatitis.

From the Journal of Brain Research Reviews:Glutathione depletioncan enhance oxidative stress and may increase levels of excitotoxic (toxins that excite neurons to the point of death) molecules, which may initiate cell death in specific nerve cell populations. Evidence of oxidative stress andreduced glutathione statusis found in Lou Gehrig’s disease, Parkinson’s disease and Alzheimer’s disease.

From the Annals of Pharmacotherapy:Glutathione is importantin DNA synthesis and repair, protein and prostaglandin synthesis, amino acid transport, metabolism of toxins and carcinogens, enhancement of immune function, prevention of oxidative cell damage and enzyme activation.

From the Journal Acta Dermato-Venereologica:Low levels of blood glutathionewere found in patients with pemphigoid, acne conglobata, polymyositis, rheumatoid arthritis, scleroderma, systemic lupus erythematosus, atopic dermatitis, eczema and psoriasis.

From the Journal of the Federation of American Societies for Experimental Biology:Intracellular glutathione enhances the immunologic function of lymphocytes (perhaps the most important immune cell line in preventing infection and cancer).Low levels of glutathionelimit the optimal functioning of T cells. Cytotoxic T cell (necessary to eliminate cancer) responses and interleukin-II-dependent functions are inhibited even by a partialdepletion of the intracellular glutathionepool.

From the journal of Ocular Pharmacological Therapy:Susceptibility of the lens nucleus to oxidative damage and loss of transparency has been shown in experimental animal models, including exposure to hyperbaric oxygen, x-ray and UVA light.Depletion of glutathioneallows the levels of oxidant to damage lens tissue and structure.

From the Journal of Laboratory and Clinical Science:An increased incidence oflow glutathione levelsin apparently healthy subjects suggests a decreased capacity to maintain metabolic and detoxification reactions that are stimulated by glutathione. The authors stated thatglutathione status, physical health, and longevity are closely related.

From the Lancet: The plasma glutathione in young, healthy adults was 0.54 umol/L; in healthy elderly it was 0.29 umol/L; in elderly outpatients it was 0.24 umol/L; and in elderly inpatients it was 0.17 umol/L. Aging results in a decrease in plasma glutathione and an increase in oxidative damage in apparently healthy individuals.

Simply put, if you want young cells and the ability to overcome disease you need to work on getting your glutathione levels up!

Tags:  food and drink  nutrition 

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